肺炎克雷伯菌在不同通气策略下生产1,3 - 丙二醇。
1,3-Propanediol production by Klebsiella pneumoniae under different aeration strategies.
作者信息
Cheng Ke-Ke, Liu De-Hua, Sun Yan, Liu Wei-Bin
机构信息
Department of Chemical Engineering, Tsinghua University, Beijing 100084, PR China.
出版信息
Biotechnol Lett. 2004 Jun;26(11):911-5. doi: 10.1023/b:bile.0000025902.44458.f4.
Abstract
1,3-Propanediol production by Klebsiella pneumoniae was studied in batch cultures under N2 flow and four airflow systems. Different byproducts were formed under different aeration conditions. An anaerobic/aerobic combined fed-batch culture was developed giving 70 g 1,3-propanediol l(-1) and 16 g 2,3-butanediol l(-1) with total diol yield of 0.6 mol(-1) glycerol.
摘要
研究了肺炎克雷伯菌在氮气流通和四种通气系统下的分批培养中1,3 - 丙二醇的生产情况。在不同的通气条件下形成了不同的副产物。开发了一种厌氧/好氧联合补料分批培养方法，可得到70 g/L的1,3 - 丙二醇和16 g/L的2,3 - 丁二醇，二醇总产率为0.6 mol/mol甘油。
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