Sadick Neil, Schecter Amy K
Weill Medical College of Cornell University, New York, New York, USA.
Dermatol Surg. 2004 Aug;30(8):1140-4. doi: 10.1111/j.1524-4725.2004.30341.x.
Nonablative laser resurfacing has been shown to improve the appearance photoaged skin. Clinical improvement has been associated with dermal collagen remodeling.
The objective was to determine the efficacy of a 1320-nm Nd:YAG laser for the treatment of photoaging hands.
Seven patients with photoaged hands received six monthly treatments with a 1320-nm Nd:YAG laser. Improvement in skin smoothness was evaluated by objective and patient assessment using a 6-point improvement scale: 1=no improvement and 6=80% to 100% improvement.
Mild to moderate improvement was achieved as determined by both objective and patient assessment. Mean improvement by objective assessment was 2.4 points. Objective improvement was noted in four of seven patients, and these patients demonstrated a mean improvement score of 3.5 points. The mean improvement by patient assessment was 3.1 points.
This case series demonstrates that the 1320-nm Nd:YAG laser with cryogen cooling can be effective for rejuvenation of photoaged hands.
非剥脱性激光换肤已被证明可改善光老化皮肤的外观。临床改善与真皮胶原重塑有关。
目的是确定1320纳米掺钕钇铝石榴石激光治疗光老化手部的疗效。
7例光老化手部患者每月接受6次1320纳米掺钕钇铝石榴石激光治疗。使用6分改善量表通过客观和患者评估来评估皮肤光滑度的改善情况：1=无改善，6=改善80%至100%。
通过客观和患者评估均实现了轻度至中度改善。客观评估的平均改善为2.4分。7例患者中有4例出现客观改善，这些患者的平均改善评分为3.5分。患者评估的平均改善为3.1分。
该病例系列表明，采用冷冻剂冷却的1320纳米掺钕钇铝石榴石激光可有效改善光老化手部的外观。
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