Bhatia Ashish C, Dover Jeffrey S, Arndt Kenneth A, Stewart Brigitte, Alam Murad
Department of Dermatology, Northwestern University Medical School, Chicago, Illinois, USA.
Dermatol Surg. 2006 Mar;32(3):346-52. doi: 10.1111/j.1524-4725.2006.32071.x.
Nonablative laser treatments have become increasingly used for the treatment of acne scarring and photoaging. While nonablative laser treatments are more convenient and relatively safer than ablative laser resurfacing, efficacy and patient satisfaction with the level of improvement of textural abnormalities in acne scarring and rhytids associated with photoaging needs further study. DESIGN/MATERIALS AND METHODS: Structured interviews were performed with 34 patients from a referral-based academic practice who each previously received a series of 6 monthly treatments with a 1,320 nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser for treatment of acne scarring or photoaging. Topical anesthesia was applied 1 hour before each treatment. Patients were interviewed at least 3 months after cessation of treatment (range 3-12 months).
Patients tolerated the treatments well. Combined results for acne scarring and photoaging patients were as follows: (a) patient satisfaction with treatment was rated at 62%, and (b) textural improvement was reported at 31% at the end of the six treatments, and 30% at the date of interview. When results were stratified by diagnosis, patient satisfaction was slightly higher for treatment of acne scarring than for photoaging. Overall degree of improvement on a 1-10 scale was 5.4 for acne scarring and 3.8 for wrinkling.
Nonablative treatment with the 1,320 nm Nd:YAG laser induced significant patient-reported improvement in both acne scarring and photoaging. The majority of patients reported satisfaction with the degree of improvement.
非剥脱性激光治疗已越来越多地用于治疗痤疮瘢痕和光老化。虽然非剥脱性激光治疗比剥脱性激光换肤更方便且相对更安全,但对于痤疮瘢痕和与光老化相关的皱纹的质地异常改善程度的疗效及患者满意度仍需进一步研究。设计/材料与方法:对来自一家基于转诊的学术机构的34例患者进行了结构化访谈,这些患者此前均接受了一系列每月1次、共6次的1320纳米钕:钇铝石榴石(Nd:YAG)激光治疗,以治疗痤疮瘢痕或光老化。每次治疗前1小时应用局部麻醉。在治疗停止后至少3个月(范围为3至12个月)对患者进行访谈。
患者对治疗耐受性良好。痤疮瘢痕和光老化患者的综合结果如下:(a)患者对治疗的满意度为62%,(b)在6次治疗结束时报告质地改善的为31%,在访谈时为30%。按诊断分层时,痤疮瘢痕治疗的患者满意度略高于光老化治疗。痤疮瘢痕在1至10分的总体改善程度为5.4,皱纹为3.8。
1320纳米Nd:YAG激光的非剥脱性治疗在痤疮瘢痕和光老化方面均使患者报告有显著改善。大多数患者对改善程度表示满意。