Karacorlu Murat, Ozdemir Hakan, Karacorlu Serra, Alacali Nilay
Istanbul Retina Institute, Istanbul, Turkey.
Int Ophthalmol. 2004 Mar;25(2):113-6. doi: 10.1023/b:inte.0000031740.85124.78.
The aim of this study is to report the clinical outcome of a diabetic patient with optic nerve head neovascularization treated with an intravitreal injection of triamcinolone acetonide. A 52-year-old patient presented with clinically significant diffuse macular edema and optic nerve head neovascularization due to proliferative diabetic retinopathy in her right eye. Despite grid laser photocoagulation in the macular region macular edema progressed and visual acuity declined. The patient received a single intravitreal injection of 4 mg triamcinolone acetonide with topical anesthesia. After injection of triamcinolone acetonide visual acuity increased and macular edema decreased. Furthermore optic nerve head neovascularization had markedly regressed. No complication was observed during follow-up period. Intravitreal injection of triamcinolone acetonide may be useful for treatment of optic nerve head neovascularization in patients with proliferative diabetic retinopathy.
本研究的目的是报告1例接受玻璃体内注射曲安奈德治疗的糖尿病性视神经乳头新生血管形成患者的临床结局。1例52岁患者右眼因增殖性糖尿病视网膜病变出现具有临床意义的弥漫性黄斑水肿和视神经乳头新生血管形成。尽管黄斑区进行了格栅样激光光凝,但黄斑水肿仍进展,视力下降。该患者在表面麻醉下接受了1次4mg曲安奈德玻璃体内注射。注射曲安奈德后,视力提高,黄斑水肿减轻。此外,视神经乳头新生血管明显消退。随访期间未观察到并发症。玻璃体内注射曲安奈德可能有助于治疗增殖性糖尿病视网膜病变患者的视神经乳头新生血管形成。