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一例接触发酵康普茶饮料后发生伴有胸腔积液和心包填塞的抗合成酶综合征(抗Jo-1型多发性肌炎)。

A case of anti-Jo1 myositis with pleural effusions and pericardial tamponade developing after exposure to a fermented Kombucha beverage.

作者信息

Derk Chris T, Sandorfi Nora, Curtis Mark T

机构信息

Division of Rheumatology, Thomas Jefferson University Hospital, Philadelphia, PA 1910, USA.

出版信息

Clin Rheumatol. 2004 Aug;23(4):355-7. doi: 10.1007/s10067-004-0890-y. Epub 2004 Apr 16.

Abstract

The pathogenesis of the idiopathic inflammatory myopathies has been postulated to be an environmental trigger causing the expression of the disease in a genetically predisposed patient. We report a case of anti-Jo1 antibody-positive myositis which was associated with pleural effusions, pericardial effusion with tamponade, and 'mechanic's hands', probably related to the consumption of a fermented Kombucha beverage. Kombucha 'mushroom', a symbiosis of yeast and bacteria, is postulated to be the trigger for our patient's disease owing to the proximity of his symptoms to the consumption of the Kombucha beverage.

摘要

特发性炎性肌病的发病机制被认为是环境触发因素在遗传易感患者中引发疾病表达。我们报告一例抗Jo1抗体阳性的肌炎病例,该病例伴有胸腔积液、心包填塞性心包积液和“技工手”,可能与饮用发酵康普茶饮料有关。康普茶“菌菇”是酵母和细菌的共生体,鉴于患者症状与饮用康普茶饮料的时间接近,推测其为引发该患者疾病的触发因素。

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