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益生菌和益生元的新科学范式。

New scientific paradigms for probiotics and prebiotics.

作者信息

Reid Gregor, Sanders M E, Gaskins H Rex, Gibson Glenn R, Mercenier Annick, Rastall Robert, Roberfroid Marcel, Rowland Ian, Cherbut Christine, Klaenhammer Todd R

机构信息

Canadian Research and Development Centre for Probiotics, Lawson Health Research Institute, 268 Grosvenor Street, London, Ontario, N6A 4V2, Canada.

出版信息

J Clin Gastroenterol. 2003 Aug;37(2):105-18. doi: 10.1097/00004836-200308000-00004.

DOI:10.1097/00004836-200308000-00004
PMID:12869879
Abstract

The inaugural meeting of the International Scientific Association for Probiotics and Prebiotics (ISAPP) was held May 3 to May 5 2002 in London, Ontario, Canada. A group of 63 academic and industrial scientists from around the world convened to discuss current issues in the science of probiotics and prebiotics. ISAPP is a non-profit organization comprised of international scientists whose intent is to strongly support and improve the levels of scientific integrity and due diligence associated with the study, use, and application of probiotics and prebiotics. In addition, ISAPP values its role in facilitating communication with the public and healthcare providers and among scientists in related fields on all topics pertinent to probiotics and prebiotics. It is anticipated that such efforts will lead to development of approaches and products that are optimally designed for the improvement of human and animal health and well being. This article is a summary of the discussions, conclusions, and recommendations made by 8 working groups convened during the first ISAPP workshop focusing on the topics of: definitions, intestinal flora, extra-intestinal sites, immune function, intestinal disease, cancer, genetics and genomics, and second generation prebiotics.

摘要

国际益生菌和益生元科学协会(ISAPP)的首届会议于2002年5月3日至5日在加拿大安大略省伦敦市举行。来自世界各地的63位学术和产业科学家齐聚一堂,讨论益生菌和益生元科学领域的当前问题。ISAPP是一个非营利组织,由国际科学家组成,其宗旨是大力支持并提高与益生菌和益生元的研究、使用及应用相关的科学诚信和尽职调查水平。此外,ISAPP重视其在促进与公众、医疗服务提供者以及相关领域科学家就所有与益生菌和益生元相关的主题进行交流方面所发挥的作用。预计这些努力将促成旨在改善人类和动物健康及福祉的最佳设计方法和产品的开发。本文是对在首届ISAPP研讨会上召开的8个工作组所进行的讨论、得出的结论及提出的建议的总结,这些工作组聚焦于以下主题:定义、肠道菌群、肠道外部位、免疫功能、肠道疾病、癌症、遗传学和基因组学以及第二代益生元。

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