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关于纯霍乱毒素不会从离体肠组织释放出类前列腺素物质的证据。

Evidence against the release of prostaglandin-like material from isolated intestinal tissue by pure cholera toxin.

作者信息

Bennett A, Charlier E M

出版信息

Prostaglandins. 1977 Mar;13(3):431-6. doi: 10.1016/0090-6980(77)90023-5.

Abstract

Prostaglandin-like material was released from finely cut guinea-pig ileum or human intestinal mucosa during incubation with Krebs solution. The tissue inactivated some significant change in release of prostaglandin-like material when pure cholera toxin was incubated with guinea-pig ileum or human intestinal mucosa. The work is discussed in relation to the action of cholera toxin in vivo.

摘要

在与克雷布斯溶液孵育期间,类前列腺素物质从切碎的豚鼠回肠或人肠黏膜中释放出来。当将纯霍乱毒素与豚鼠回肠或人肠黏膜一起孵育时,组织中类前列腺素物质释放的某些显著变化被消除。本文结合霍乱毒素在体内的作用对该研究进行了讨论。

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引用本文的文献

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Effect of cholera toxin on the production of eicosanoids by rat jejunum.
Br J Pharmacol. 1987 Sep;92(1):149-52. doi: 10.1111/j.1476-5381.1987.tb11306.x.

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