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对来自土耳其的1098例急性中毒病例的流行病学评估。

An epidemiological evaluation of 1098 acute poisoning cases from Turkey.

作者信息

Akkas Meltem, Coskun Figen, Ulu Nadir, Sivri Bulent

机构信息

Hacettepe University Faculty of Medicine, Department of Emergency Medicine, Ankara, Turkey.

出版信息

Vet Hum Toxicol. 2004 Aug;46(4):213-5.

Abstract

This study evaluated the characteristics of orally poisoned patients admitted to our emergency department (ED) between January 1, 1998 and February 28, 2002. This study included 1098 patients. Poisoning cases annualy accounted for 0.5-1.3% of total patient admission during this period. The average age of the patients was 26y old. Poisoning was particulary common in students and housewives. Poisoning cases presented to the ED most commonly between 6 pm and 12 am (38%). More than half of study patients (52%) were admitted to the ED within 2 h of exposure. The incidence of concomitant alcohol intake with another intoxicant was 11%. The ingested drugs were 32% various antidepressants, 23% paracetamol, 20% analgesics (excluding paracetamol and salicylates), 10% antibiotics, 9% benzodiazepines, 7% salicylates and 7% cardiovascular drugs. Most patients received at least 1 of the following treatments: gastric lavage, oral activated charcoal, iv hydration, or diuresis. Thirty-two percent of patients were hospitalized beyond 24 h and 68% of were discharged within 24 h. The mortality rate of the overall cohort was < 1%. Psychiatric consultation was obtained for 55% of patients.

摘要

本研究评估了1998年1月1日至2002年2月28日期间入住我院急诊科(ED)的口服中毒患者的特征。本研究纳入了1098例患者。在此期间,中毒病例每年占总住院患者的0.5 - 1.3%。患者的平均年龄为26岁。中毒在学生和家庭主妇中尤为常见。中毒病例最常于下午6点至午夜12点之间被送至急诊科(占38%)。超过一半的研究患者(52%)在接触毒物后2小时内被送至急诊科。同时摄入酒精和另一种毒物的发生率为11%。所摄入的药物中,各种抗抑郁药占32%,对乙酰氨基酚占23%,镇痛药(不包括对乙酰氨基酚和水杨酸盐)占20%,抗生素占10%,苯二氮䓬类药物占9%,水杨酸盐占7%,心血管药物占7%。大多数患者接受了以下至少一种治疗:洗胃、口服活性炭、静脉补液或利尿。32%的患者住院超过24小时,68%的患者在24小时内出院。整个队列的死亡率<1%。55%的患者接受了精神科会诊。

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