Soderberg Kjell, Kuusinen Petri, Mathieu Laurence, Hall Alan H
Medical Service, Avesta Polarit, Torshalla, Sweden.
Vet Hum Toxicol. 2004 Aug;46(4):216-8.
Accidental hydrofluoric acid (HF) splashes often occur in industrial settings. HF easily penetrates into tissues by initial acid action allowing fluoride ions to penetrate deeply, chelating calcium and magnesium. Resultant hypocalcemia and hypomagnesemia can be fatal. This report describes the utilization of Hexafluorine--a hypertonic, amphoteric, chelating decontamination solution--in workplaces where water decontamination followed by calcium gluconate inunction failed to prevent HF burns and systemic toxicity. Between 1998 and 1999, 16 cases of ocular and dermal HF splashes with either 70% HF or 6% HF/15% nitric acid (HNO3) were decontaminated with Hexafluorine at the worksite. HF burns did not develop and medical treatment other than initial decontamination was not reQuired in 12/16 (75%). In 7/16 (44%) cases, lost work time corresponded to duration of hospital observation (mean < 1 d).
意外氢氟酸(HF)溅泼事故在工业环境中时常发生。氢氟酸通过最初的酸作用轻易渗透到组织中,使氟离子得以深入渗透,螯合钙和镁。由此产生的低钙血症和低镁血症可能是致命的。本报告描述了在水冲洗后涂抹葡萄糖酸钙仍无法预防氢氟酸灼伤和全身毒性的工作场所中,使用六氟灵(一种高渗、两性、螯合去污溶液)的情况。1998年至1999年间,16例眼部和皮肤被70%氢氟酸或6%氢氟酸/15%硝酸(HNO₃)溅泼的病例在工作现场用六氟灵进行了去污处理。16例中有12例(75%)未出现氢氟酸灼伤,除初始去污外无需其他医疗治疗。在16例中的7例(44%)中,误工时间与住院观察时间相符(平均<1天)。