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[1型糖尿病女童的生殖器感染]

[Genital infections in girls with type 1 diabetes].

作者信息

Petrova Ch, Shentov B, Tanchev S, Mikhaĭlov V, Sredkova M, POpova V

出版信息

Akush Ginekol (Sofiia). 2004;43(4):21-5.

Abstract

The aim of the study was to investigate the relation between genital infections (frequency, etiology, clinical presentation) among girls with type 1 diabetes and some factors as age of the girls, duration and metabolic control of diabetes. Forty-three girls with type 1 diabetes and twelve healthy girls for controls were involved in the study. Methods used are: genital tract inspection, direct microscopy and cultures from genital discharge and urine. Glycaemic control in the diabetic girls was assessed by measuring total glycosylated haemoglobin. The results show vulvovaginal candidiasis in 27 (62.8%) in diabetic girls versus 2 (16.6%) in controls (p < 0.01). There was clear prevalence of non-albicans Candida species. Concomitant infection with bacterial pathogens were proved in only 6 (13.9%) of diabetic girls and 1 (8.5%) of the controls. The clinical presentation of genital candidiasis was vulvovaginitis and most of the affected diabetic girls (88.9%) were in puberty period. There was no relation between duration and metabolic control of diabetes and genital infections.

摘要

该研究的目的是调查1型糖尿病女孩的生殖器感染(频率、病因、临床表现)与一些因素之间的关系,这些因素包括女孩的年龄、糖尿病病程和代谢控制情况。43名1型糖尿病女孩和12名健康女孩作为对照参与了该研究。使用的方法有:生殖道检查、直接显微镜检查以及从阴道分泌物和尿液中进行培养。通过测量糖化血红蛋白总量评估糖尿病女孩的血糖控制情况。结果显示,糖尿病女孩中有27例(62.8%)患外阴阴道念珠菌病,而对照组中仅有2例(16.6%)患病(p<0.01)。非白色念珠菌属明显占优势。仅6例(13.9%)糖尿病女孩和1例(8.5%)对照女孩被证实同时感染细菌病原体。生殖器念珠菌病的临床表现为外阴阴道炎,大多数受影响的糖尿病女孩(88.9%)处于青春期。糖尿病的病程和代谢控制与生殖器感染之间没有关系。

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