Srinivasan Ramesh, Tutuian Radu, Schoenfeld Philip, Vela Marcelo F, Castell June A, Isaac Thomas, Galaria Irfan, Katz Philip O, Castell Donald O
University of Texas Medical Branch, Galveston, Texas, USA.
J Clin Gastroenterol. 2004 Sep;38(8):651-7. doi: 10.1097/01.mcg.0000135364.12794.e5.
An observational, cross-sectional, epidemiology study of the characteristics of GERD in a large northeast urban population was performed using a self-responding 84-question survey. Four-hundred and ten surveys were completed from a population sample with demographics comparable to those of the 1990 US Census data.
No differences in heartburn frequency (monthly) were found between white or black, male or female respondents. Heartburn was significantly (P = 0.01) less common in those over age 60 (36.9%) than in young (47.7%) or middle-age (57.3%) respondents. Impact of heartburn on social activities was less (P = 0.002) in the over 60 group (4.9%) compared with the young (19.3%) or middle-age (20.0%) groups. Although 49.8% of respondents were familiar to the term GERD, few were aware that swallowing difficulty (17.3%), asthma (9.3%) or hoarseness (11.5%) were possible symptoms and similar numbers considered stroke (33.2%) and cancer (31.7%) to be complications of GERD.
Frequency of GERD symptoms in the United States is unaffected by gender or race but is lower in the elderly.
采用一份含84个问题的自填式调查问卷，对美国东北部一个大型城市人口中的胃食管反流病（GERD）特征进行了一项观察性横断面流行病学研究。从一个人口样本中完成了410份调查问卷，该样本的人口统计学特征与1990年美国人口普查数据的特征相当。
在白人或黑人、男性或女性受访者之间，烧心频率（每月）未发现差异。60岁以上人群中烧心的发生率（36.9%）显著低于年轻（47.7%）或中年（57.3%）受访者（P = 0.01）。与年轻组（19.3%）或中年组（20.0%）相比，60岁以上组中烧心对社交活动的影响较小（P = 0.002）（4.9%）。尽管49.8%的受访者熟悉GERD这个术语，但很少有人意识到吞咽困难（17.3%）、哮喘（9.3%）或声音嘶哑（11.5%）可能是GERD的症状，并且有相似比例的人认为中风（33.2%）和癌症（31.7%）是GERD的并发症。
在美国，GERD症状的发生率不受性别或种族影响，但在老年人中较低。
