Cosmelli Diego, David Olivier, Lachaux Jean-Philippe, Martinerie Jacques, Garnero Line, Renault Bernard, Varela Francisco
Cognitive Neuroscience and Brain Imaging Laboratory, CNRS UPR 640, Hôpital de La Salpêtrièrie, 75651 Paris Cedex 13, France.
Neuroimage. 2004 Sep;23(1):128-40. doi: 10.1016/j.neuroimage.2004.05.008.
We present here ongoing patterns of distributed brain synchronous activity that correlate with the spontaneous flow of perceptual dominance during binocular rivalry. Specific modulation of the magnetoencephalographic (MEG) response evoked during conscious perception of a frequency-tagged stimulus was evidenced throughout rivalry. Estimation of the underlying cortical sources revealed, in addition to strong bilateral striate and extrastriate visual cortex activation, parietal, temporal pole and frontal contributions. Cortical activity was significantly modulated concomitantly to perceptual alternations in visual cortex, medial parietal and left frontal regions. Upon dominance, coactivation of occipital and frontal regions, including anterior cingulate and medial frontal areas, was established. This distributed cortical network, as measured by phase synchrony in the frequency tag band, was dynamically modulated in concert with the perceptual dominance of the tagged stimulus. While the anteroposterior pattern was recurrent through subjects, individual variations in the extension of the network were apparent.
我们在此展示了与双眼竞争期间感知优势的自发流动相关的分布式脑同步活动的持续模式。在整个竞争过程中，都证明了在有意识地感知频率标记刺激时诱发的脑磁图（MEG）反应的特定调制。对潜在皮质源的估计显示，除了强烈的双侧纹状和纹外视觉皮质激活外，还有顶叶、颞极和额叶的贡献。皮质活动在视觉皮质、内侧顶叶和左额叶区域与感知交替同时受到显著调制。在优势期，枕叶和额叶区域（包括前扣带回和内侧额叶区域）建立了共同激活。通过频率标记频段中的相位同步测量的这个分布式皮质网络，与标记刺激的感知优势协同动态调制。虽然前后模式在受试者中反复出现，但网络范围的个体差异很明显。
