Braun J, Treutner K H, Winkeltau G, Heidenreich U, Lerch M M, Schumpelick V
Department of Surgery, Medical Faculty, Rhenish-Westphalian Technical University Aachen, Federal Republic of Germany.
Am J Surg. 1992 Apr;163(4):407-12. doi: 10.1016/0002-9610(92)90042-p.
Between 1977 and 1987, 519 patients underwent operation for rectal carcinoma. Sixty-three patients underwent intersphincteric resection with direct coloanal anastomosis (CAA), and 77 had an abdominoperineal resection (APR). Curative surgery was achieved in 57 and 65 patients, respectively. Both groups were comparable regarding age, stage of tumors, and localization of tumors. During the mean period of 6.7 years (range: 3 to 13.6 years), all patients were examined according to a predefined follow-up plan. From those patients with curative surgery, 11% presented with pelvic recurrence and 33% with distant metastases after coloanal anastomosis; the rates of recurrence and distant metastases after APR were 17% and 35%, respectively. The corrected 5-year survival rates were 62% following CAA and 53% following APR. Eighty-five percent of the patients with CAA reported good functional results regarding anal continence. Our study demonstrates that the intersphincteric resection with CAA is a valuable surgical technique for rectal carcinoma with the benefit of preservation of continence. It is suitable for neoplasms with high- and medium-grade differentiation (G1 to G2) and a localization that allows a minimum distal clearence of 3 cm.
1977年至1987年间,519例患者接受了直肠癌手术。63例患者接受了括约肌间切除术并直接进行结肠肛管吻合术(CAA),77例患者接受了腹会阴联合切除术(APR)。分别有57例和65例患者实现了根治性手术。两组在年龄、肿瘤分期和肿瘤定位方面具有可比性。在平均6.7年(范围:3至13.6年)的时间里,所有患者均按照预先制定的随访计划进行检查。在接受根治性手术的患者中,结肠肛管吻合术后有11%出现盆腔复发,33%出现远处转移;APR术后复发和远处转移率分别为17%和35%。CAA术后校正的5年生存率为62%,APR术后为53%。85%接受CAA手术的患者报告在肛门节制方面功能良好。我们的研究表明,括约肌间切除术联合CAA是一种治疗直肠癌的有价值的手术技术,其优点是保留了节制功能。它适用于高分化和中分化(G1至G2)且肿瘤定位允许至少3 cm远端切缘的肿瘤。