Leszczyński Rafał, Gierek-Lapińska Ariadna, Formińska - Kapuścik Maria
1st Department of Ophthalmology, Medical University of Silesia, 40-014 Katowice, Poland.
Med Sci Monit. 2004 Sep;10(9):CR542-8. Epub 2004 Aug 20.
The purpose of this study was to evaluate the results obtained by using transscleral cyclophotocoagulation (TSCPC) in the treatment of refractory secondary glaucoma. Our study attempted to assess the functional effects of TSCPC in different types of secondary glaucoma.
MATERIAL/METHODS: We studied 83 eyes in 81 patients: 52 men and 29 women, aged 9-88 years old (mean 52.8+/-21.85). Contact transscleral cyclophotocoagulation was performed with an OcuLight SLx photocoagulator using a G probe. The follow-up period was 12 months. All the eyes were photographed for documentation of details.
The mean intraocular pressure (IOP) significantly decreased, from 46+/-12 mmHg at baseline to 18+/-6.4 mmHg (p<0.05) at the end of the 12-month observation period. Average visual acuity showed no statistically significant changes. The number of TSCPC procedures ranged from 1 to 4. The number of anti-glaucoma drugs decreased from 2.8+/-0.9 to 1.9+/-0.9 (p<0.05). The T/E coefficient was the lowest in pediatric secondary glaucoma (p<0.05). Most of the severe complications developed in neovascular glaucoma (p<0.05).
Contact transscleral cyclophotocoagulation effectively decreases intraocular pressure and the number of anti-glaucoma medications and also alleviates pain in the majority of patients with severe secondary glaucoma. Patients with neovascular glaucoma are at the highest risk of severe complications following TSCPC. TSCPC was the least effective in patients with refractory pediatric glaucoma. Since there is a risk of photocoagulative damage to the sclera and conjunctiva, areas of hyperpigmentation, hemorrhage and scleral thinning should be avoided.
本研究旨在评估经巩膜睫状体光凝术(TSCPC)治疗难治性继发性青光眼的效果。我们的研究试图评估TSCPC在不同类型继发性青光眼中的功能作用。
材料/方法:我们研究了81例患者的83只眼睛:52例男性和29例女性,年龄9 - 88岁(平均52.8±21.85岁)。使用G探头的OcuLight SLx光凝器进行接触式经巩膜睫状体光凝术。随访期为12个月。所有眼睛均拍照以记录详细情况。
平均眼压显著降低,从基线时的46±12 mmHg降至12个月观察期末的18±6.4 mmHg(p<0.05)。平均视力无统计学显著变化。TSCPC手术次数为1至4次。抗青光眼药物数量从2.8±0.9降至1.9±0.9(p<0.05)。小儿继发性青光眼中的T/E系数最低(p<0.05)。大多数严重并发症发生在新生血管性青光眼中(p<0.05)。
接触式经巩膜睫状体光凝术能有效降低眼压和减少抗青光眼药物数量,还能缓解大多数严重继发性青光眼患者的疼痛。新生血管性青光眼患者在TSCPC后发生严重并发症的风险最高。TSCPC在难治性小儿青光眼中效果最差。由于存在光凝损伤巩膜和结膜的风险,应避免出现色素沉着、出血和巩膜变薄的区域。