Kahn M F, Chamot A M
Université Paris VII, Hôpital Bichat, France.
Rheum Dis Clin North Am. 1992 Feb;18(1):225-46.
SAPHO (synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome put together osteoarticular lesions described separately under numerous denominations, such as multifocal osteomyelitis, pustulotic arthroosteitis, acne rheumatism. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is the cornerstone of this new syndrome, which also has links with spondyloarthropathies and plain psoriasis.
SAPHO(滑膜炎、痤疮、脓疱病、骨质增生、骨炎)综合征整合了多种不同名称下分别描述的骨关节病变,如多灶性骨髓炎、脓疱性关节骨炎、痤疮风湿症。无菌性炎性骨病变与嗜中性皮病的关联是这一新综合征的基石,该综合征还与脊柱关节病及寻常型银屑病有关。