周效磺胺-乙胺嘧啶和甲氟喹治疗秘鲁亚马逊流域非复杂性恶性疟的疗效
Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru.
作者信息
Magill Alan J, Zegarra Jorge, Garcia Coralith, Marquiño Wilmer, Ruebush Trenton K
机构信息
Naval Medical Research Center Detachment Lima, Peru.
出版信息
Rev Soc Bras Med Trop. 2004 May-Jun;37(3):279-81. doi: 10.1590/s0037-86822004000300015.
Abstract
In vivo antimalarial drug efficacy studies of uncomplicated Plasmodium falciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of resistance to mefloquine.
摘要
在秘鲁与巴西和哥伦比亚接壤的亚马逊河流域一个偏远地区，针对非复杂性恶性疟原虫疟疾开展的体内抗疟药物疗效研究显示，对磺胺多辛-乙胺嘧啶的RII/RIII耐药率超过50%，但未发现对甲氟喹耐药的证据。
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