圣罗勒（Ocimum sanctum Linn.）及其培养物的抗惊厥潜力。
Anticonvulsant potential of holy basil, Ocimum sanctum Linn., and its cultures.
作者信息
Jaggi Raj K, Madaan Reecha, Singh Balbir
机构信息
University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India.
出版信息
Indian J Exp Biol. 2003 Nov;41(11):1329-33.
Callus cultures from stem of O. sanctum were induced on slightly modified Murashige and Skoog's (MS) medium and supplemented with 2,4-dichlorophenoxyacetic acid (2,4-D, 1-2 ppm) and kinetin (kn, 1 ppm). Different extractives of stem, leaf and stem callus of O. sanctum were tested for anticonvulsant activity against standard drug phenytoin using maximal electroshock (MES) model. Ethanol and chloroform extractives of stem, leaf and stem calli were effective in preventing tonic convulsions induced by transcorneal electroshock.
在略微改良的Murashige和Skoog（MS）培养基上诱导神圣罗勒茎的愈伤组织培养物，并添加2,4 - 二氯苯氧乙酸（2,4 - D，1 - 2 ppm）和激动素（kn，1 ppm）。使用最大电休克（MES）模型，测试神圣罗勒茎、叶和茎愈伤组织的不同提取物对标准药物苯妥英的抗惊厥活性。茎、叶和茎愈伤组织的乙醇和氯仿提取物可有效预防经角膜电休克诱导的强直性惊厥。
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