McFaul C D, Vitone L J, Campbell F, Azadeh B, Hughes M L, Garvey C J, Ghaneh P, Neoptolemos J P
Department of Surgery, Royal Liverpool University Hospital, Liverpool, UK.
Pancreatology. 2004;4(6):533-7; discussion 537-8. doi: 10.1159/000080528. Epub 2004 Aug 30.
Pancreatic hamartoma is a rare benign lesion and may be mistaken for a malignancy, as demonstrated by two cases. The first case was a 29-year-old man who presented with a 7-month history of intermittent upper abdominal pain, nausea and vomiting and a 15-kg weight loss. CT and MRI revealed a mass in the head of the pancreas. The second case was a 62-year-old man who presented with a 2-year history of intermittent abdominal pain, vomiting and a 25-kg weight loss. Although positron emission tomography was normal, CT revealed thickening of the duodenal wall and endoluminal ultrasonography revealed a tumour in the head of the pancreas. Both patients recovered from uneventful Kausch-Whipple pancreatoduodenectomy (in the first patient, it was pylorus-preserving), and in each case the histological diagnosis was hamartoma. Pancreatic hamartoma can present with vague, non-specific symptoms which, despite modern diagnostic tools, can be difficult to diagnose. Surgical resection with histopathological examination is required to confirm the diagnosis.
胰腺错构瘤是一种罕见的良性病变，有两例病例表明其可能被误诊为恶性肿瘤。第一例是一名29岁男性，有7个月间歇性上腹部疼痛、恶心和呕吐病史，体重减轻15千克。CT和MRI显示胰腺头部有肿块。第二例是一名62岁男性，有2年间歇性腹痛、呕吐病史，体重减轻25千克。尽管正电子发射断层扫描结果正常，但CT显示十二指肠壁增厚，腔内超声检查显示胰腺头部有肿瘤。两名患者均顺利接受了保留幽门的Kausch-Whipple胰十二指肠切除术（第一例患者），每例组织学诊断均为错构瘤。胰腺错构瘤可表现为模糊、非特异性症状，尽管有现代诊断工具，仍可能难以诊断。需要进行手术切除并进行组织病理学检查以确诊。
