Pans A, Pierard G E
Department of Abdominal Surgery, University of Liège, Belgium.
Eur Surg Res. 1992;24(1):54-60. doi: 10.1159/000129188.
We compared the tissue response to the intraperitoneal implantation of three different prostheses (Gore-Tex, Mersilène, Vicryl-Mersilène) used to repair abdominal wall defects in rats. Vicryl-Mersilène is a new experimental prosthesis made of Dacron (Mersilène) coated with absorbable polyglactin (Vicryl). The least amount of adhesions to omentum and gut was found with Mersilène. Gore-Tex was responsible for the accumulation of neutrophils rather than macrophages mostly collected in close contact with Mersilène and Vicryl-Mersilène. Fibrosis, evaluated by histology and computerized morphometry, was mostly found with Vicryl-Mersilène. This should allow a better incorporation of Mersilène and a tighter anchorage to the abdominal wall, after Vicryl resorption.
我们比较了用于修复大鼠腹壁缺损的三种不同假体（戈尔特斯、梅丝纶、维可牢尼龙线-梅丝纶）腹腔内植入后的组织反应。维可牢尼龙线-梅丝纶是一种新型实验性假体，由涂有可吸收聚乙醇酸（维可牢尼龙线）的涤纶（梅丝纶）制成。梅丝纶与大网膜和肠道的粘连最少。戈尔特斯导致中性粒细胞聚集，而巨噬细胞大多聚集在与梅丝纶和维可牢尼龙线-梅丝纶紧密接触的部位。通过组织学和计算机形态测量评估的纤维化，在维可牢尼龙线-梅丝纶中最为常见。维可牢尼龙线吸收后，这应能使梅丝纶更好地融合，并更紧密地锚定在腹壁上。
