Gross Harald, Reitner Joachim, König Gabriele M
Pharmazeutische Biologie, Universität Bonn, Nussallee 6, 53115 Bonn, Germany.
Naturwissenschaften. 2004 Sep;91(9):441-6. doi: 10.1007/s00114-004-0552-6. Epub 2004 Sep 1.
Chemical investigation of the deepwater sponge Macandrewia azorica, collected from the flanks of the Gettysburg and Ormonde Sea Mount, North Atlantic, from a depth of 600 m, has led to the isolation of a new sterol with an unusual side chain (1), along with S-methylergothioneine (2). The structures of compounds 1 and 2 were established by employing spectroscopic techniques (NMR, MS, UV, IR and polarimetry). This is the first report of metabolites of a sponge belonging to the genus Macandrewia.
对采自北大西洋葛底斯堡和奥蒙德海山侧翼600米深处的深水海绵Azorica Macandrewia进行化学研究，分离出一种具有不寻常侧链的新甾醇（1）以及S-甲基麦角硫因（2）。化合物1和2的结构通过光谱技术（核磁共振、质谱、紫外、红外和旋光测定法）确定。这是关于Macandrewia属海绵代谢产物的首次报道。
