从海洋海绵 Phyllospongia foliascens 中分离得到的倍半萜和一种新固醇。

Sesterterpenes and a new sterol from the marine sponge Phyllospongia foliascens.

机构信息

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, China.

出版信息

Molecules. 2010 Feb 5;15(2):834-41. doi: 10.3390/molecules15020834.

DOI:10.3390/molecules15020834

PMID:20335950

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6257178/

Abstract

A new scalarane sesterterpene, phyllofolactone M (1), and a new sterol, (24E)-5alpha,6alpha-epoxystigmasta-7,24(28)-dien-3beta-ol (3), together with a known sesterterpene, phyllofolactone B (2), were isolated from the South China Sea sponge Phyllospongia foliascens. Their structures were elucidated by spectroscopic analysis and comparison with known compounds. In addition, previous NMR data assignments for the known sesterterpene phyllofolactone B (2) were revised.

摘要

从南海海绵 Phyllospongia foliascens 中分离得到一个新的倍半萜甾体化合物， Phyllofolactone M（1）和一个新的甾醇，（24E）-5α，6α-环氧麦角甾-7,24（28）-二烯-3β-醇（3），以及一个已知的倍半萜甾体化合物， Phyllofolactone B（2）。它们的结构通过光谱分析和与已知化合物的比较来阐明。此外，还修正了先前已知倍半萜甾体化合物 Phyllofolactone B（2）的 NMR 数据归属。