Doherty Colin P, West W Caroline, Dilley Laura C, Shattuck-Hufnagel Stefanie, Caplan David
Neuropsychology Laboratory and MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.
Hum Brain Mapp. 2004 Oct;23(2):85-98. doi: 10.1002/hbm.20042.
We examined changes in fMRI BOLD signal associated with question/statement judgments in an event-related paradigm to investigate the neural basis of processing one aspect of intonation. Subjects made judgments about digitized recordings of three types of utterances: questions with rising intonation (RQ; e.g., "She was talking to her father?"), statements with a falling intonation (FS; e.g., "She was talking to her father."), and questions with a falling intonation and a word order change (FQ; e.g., "Was she talking to her father?"). Functional echo planar imaging (EPI) scans were collected from 11 normal subjects. There was increased BOLD activity in bilateral inferior frontal and temporal regions for RQ over either FQ or FS stimuli. The study provides data relevant to the location of regions responsive to intonationally marked illocutionary differences between questions and statements.
我们在一个事件相关范式中研究了与问题/陈述判断相关的功能磁共振成像（fMRI）血氧水平依赖（BOLD）信号变化，以探究语调处理一个方面的神经基础。受试者对三种类型话语的数字化录音进行判断：升调问题（RQ；例如，“她在和她父亲说话吗？”）、降调陈述（FS；例如，“她在和她父亲说话。”）以及降调且语序改变的问题（FQ；例如，“她在和她父亲说话吗？”）。对11名正常受试者进行了功能性回波平面成像（EPI）扫描。与FQ或FS刺激相比，RQ在双侧额下回和颞叶区域的BOLD活动增加。该研究提供了与对问题和陈述之间语调标记的言外差异有反应的区域位置相关的数据。
