Meinkoth Katrina R, Morton Rebecca J, Meinkoth James H
Office of Admissions and Recruitment, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
J Am Vet Med Assoc. 2004 Aug 15;225(4):545-7, 538. doi: 10.2460/javma.2004.225.545.
A 4-year-old spayed female Irish Setter was examined because of acute onset of lethargy, anorexia, and weakness. The dog had eaten an adult rabbit 36 hours earlier. Tularemia was suspected because of the rabbit exposure; however, other common diseases characterized by fever, malaise, and lymphadenopathy of acute onset were also considered (ie, ehrlichiosis and Rocky Mountain spotted fever). The dog was treated with doxycycline (5 mg/kg [2.3 mg/lb], PO, q 24 h) for 14 days as well as supportive treatment with a balanced electrolyte solution (lactated Ringer's solution [200 mL, SC]). The diagnosis was first established by results of bacteriologic cultures of fine-needle aspirates obtained from lymph nodes and confirmed by results of ELISA and a polymerase chain reaction assay Successful and timely antemortem diagnosis of tularemia in dogs can be accomplished through lymph node aspiration and bacteriologic culture.
一只4岁已绝育的雌性爱尔兰雪达犬因突然出现嗜睡、厌食和虚弱而接受检查。该犬在36小时前吃了一只成年兔子。由于接触过兔子，怀疑患有兔热病；然而，也考虑了其他以急性发热、不适和淋巴结病为特征的常见疾病（即埃立克体病和落基山斑疹热）。该犬接受了14天的强力霉素治疗（5毫克/千克[2.3毫克/磅]，口服，每24小时一次）以及用平衡电解质溶液（乳酸林格氏液[200毫升，皮下注射]）进行支持治疗。诊断首先通过从淋巴结获取的细针抽吸物的细菌培养结果得以确立，并通过酶联免疫吸附测定和聚合酶链反应检测结果得到证实。犬兔热病的成功且及时的生前诊断可通过淋巴结抽吸和细菌培养来完成。
