Vieira Helena L A, Freire Patrick, Arraiano Cecília M
Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, 2781-901 Oeiras, Portugal.
Appl Environ Microbiol. 2004 Sep;70(9):5682-4. doi: 10.1128/AEM.70.9.5682-5684.2004.
Biofilm physiology is established under a low growth rate. The morphogene bolA is mostly expressed under stress conditions or in stationary phase, suggesting that bolA could be implicated in biofilm development. In order to verify this hypothesis, we tested the effect of bolA on biofilm formation. Overexpression of bolA induces biofilm development, while bolA deletion decreases biofilms.
生物膜生理学是在低生长速率下建立的。形态发生基因bolA大多在应激条件下或稳定期表达，这表明bolA可能与生物膜形成有关。为了验证这一假设，我们测试了bolA对生物膜形成的影响。bolA的过表达诱导生物膜形成，而bolA的缺失则减少生物膜。
