Woodhouse Christopher R J, Robertson William G
The Institute of Urology and Nephrology, University College, 48 Riding House Street, London W1W 7EY, UK.
World J Urol. 2004 Sep;22(3):215-21. doi: 10.1007/s00345-004-0437-5. Epub 2004 Sep 3.
The incidence of stones in patients with enterocystoplasty is reported as 12-52.5%. Most patients will have multiple physical factors such as immobility, need for self catheterisation and poor urine drainage, so that it is not certain that an intestinal reservoir is the cause of stones on its own. There is little or no evidence that mucus is an aetiological factor. Foreign bodies in the reservoir, such as staples, increase the risk of stone formation from 13% to 43%. Stones require surgical removal. Minimally invasive techniques may be used for small stones. A low velocity disintegrator is required so that fragments are not propelled into the intestinal mucosa. Stones are infective in origin in 86% of cases, but 14% are sterile. Metabolic screen shows that 80% of patients have risk factors for at least three different types of stone. All patients have raised pH (mean 6.93) and hypocitraturia. Raised serum and urinary calcium, hyperoxaluria and hyperuricosuria are found in up to 33% of patients.
行膀胱扩大术患者的结石发病率据报道为12% - 52.5%。大多数患者会有多种身体因素,如活动不便、需要自行导尿以及尿液引流不畅,因此尚不能确定肠膀胱自身就是结石的病因。几乎没有证据表明黏液是一个病因学因素。膀胱内的异物,如吻合钉,会使结石形成风险从13%增加到43%。结石需要手术取出。对于小结石可采用微创技术。需要使用低速碎石器,以免碎片被推进肠黏膜。86%的病例中结石起源于感染,但14%为无菌性结石。代谢筛查显示,80%的患者至少有三种不同类型结石的风险因素。所有患者的pH值均升高(平均6.93)且枸橼酸盐尿减少。高达33%的患者存在血清和尿钙升高、高草酸尿症和高尿酸尿症。