Anuradha S, Arora Sandeep, Mehrotra S, Arora A, Kar P
Department of Medicine, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India.
Ren Fail. 2004 May;26(3):329-32. doi: 10.1081/jdi-200026722.
We report a case of systemic poisoning with para-phenylenediamine (PPD) presenting with characteristic features of severe angioneurotic edema, rhabdomyolysis and intravascular hemolysis with hemoglobinuria culminating in acute renal failure. Though rare in western countries, such poisoning is not uncommon in East Africa, Indian subcontinent and Middle East countries. We discuss here the clinical features and key management issues of systemic PPD poisoning.
我们报告一例对苯二胺(PPD)全身中毒病例,其表现为严重血管神经性水肿、横纹肌溶解、血管内溶血伴血红蛋白尿等特征性表现,最终导致急性肾衰竭。尽管在西方国家这种中毒情况罕见,但在东非、印度次大陆和中东国家并不少见。我们在此讨论全身性PPD中毒的临床特征和关键管理问题。