Pilotto Louis S, Smith Brian J, Heard Adrian R, McElroy Heather J, Weekley Josephine, Bennett Paul
Department of General Practice, Flinders University, South Australia, Australia.
Respirology. 2004 Aug;9(3):356-62. doi: 10.1111/j.1440-1843.2004.00589.x.
The aim of this study was to assess the ability of nurse-run asthma clinics based in general practice compared with usual medical care to produce at least a moderate improvement in the quality of life of adults with asthma.
A randomized controlled trial involving 80 asthma clinic and 90 usual medical care asthma participants, aged 18 years and older was conducted in 11 general practices in Adelaide. The main outcome measure was the St George's respiratory questionnaire (SGRQ), from which quality-of-life scores were used to assess therapeutic benefit. Lung function measurements and health services utilization data were also collected.
One hundred and fifty-three participants (90%) were reviewed at follow up after 6-9 months. There was little difference between groups in baseline measures or for the 6-month follow-up outcomes, including the mean difference in total SGRQ scores (-0.5, 95% confidence interval (CI) -4.0, 2.9) and the mean difference in percentage predicted FEV(1) (2.3%, 95% CI -0.7, 5.3 pre-bronchodilator; 0.4%, 95% CI -5.1, 5.9 post-bronchodilator). Trends in health services utilization were noted.
Nurse-run asthma clinics based in general practice and usual medical care were similar in their effects on quality of life and lung function in adults. These findings cannot be generalized to hospital outpatients and other clinics that manage more severe asthmatic patients.
本研究旨在评估与常规医疗护理相比,以全科医疗为基础的护士主导的哮喘诊所能否至少使成年哮喘患者的生活质量得到中度改善。
在阿德莱德的11家全科医疗机构中进行了一项随机对照试验,纳入了80名哮喘诊所的参与者和90名接受常规医疗护理的哮喘参与者,年龄均在18岁及以上。主要结局指标是圣乔治呼吸问卷(SGRQ),用其生活质量评分来评估治疗效果。还收集了肺功能测量数据和卫生服务利用数据。
6至9个月后,153名参与者(90%)接受了随访。两组在基线测量或6个月随访结局方面差异不大,包括SGRQ总分的平均差异(-0.5,95%置信区间(CI)-4.0,2.9)以及预计第一秒用力呼气容积(FEV(1))百分比的平均差异(支气管扩张剂使用前为2.3%,95%CI -0.7,5.3;支气管扩张剂使用后为0.4%,95%CI -5.1,5.9)。注意到了卫生服务利用的趋势。
以全科医疗为基础的护士主导的哮喘诊所和常规医疗护理对成年患者生活质量和肺功能的影响相似。这些研究结果不能推广到医院门诊患者以及管理更严重哮喘患者的其他诊所。