儿童单纯疱疹病毒性角膜炎
Herpes simplex virus keratitis in children.
作者信息
Chong Eva-Marie, Wilhelmus Kirk R, Matoba Alice Y, Jones Dan B, Coats David K, Paysse Evelyn A
机构信息
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, 6565 Fannin Street, Houston, TX 77030, USA.
出版信息
Am J Ophthalmol. 2004 Sep;138(3):474-5. doi: 10.1016/j.ajo.2004.04.027.
PURPOSE
To describe the spectrum and recurrence of herpes simplex virus (HSV) keratitis in children and adolescents.
DESIGN
Retrospective cohort study.
METHODS
Twenty-three patients younger than age 16 years were diagnosed with HSV keratitis at one institution.
RESULTS
All children presented with dendritic or punctate epithelial keratitis, and stromal keratitis occurred concurrently with epithelial keratitis in 14 patients (61%). Six patients (26%) had bilateral HSV keratitis. Eleven patients (48%) developed recurrent HSV keratitis at a median of 15 months after the first documented episode. Amblyopia occurred in three children.
CONCLUSION
Children with herpetic keratitis may have bilateral ocular involvement and are at risk for recurrent keratitis and amblyopia.
目的
描述儿童和青少年单纯疱疹病毒（HSV）角膜炎的范围及复发情况。
设计
回顾性队列研究。
方法
在一家机构中，23名16岁以下患者被诊断为HSV角膜炎。
结果
所有儿童均表现为树枝状或点状上皮性角膜炎，14例（61%）患者基质性角膜炎与上皮性角膜炎同时发生。6例（26%）患者为双侧HSV角膜炎。11例（48%）患者在首次记录发病后的中位时间15个月出现复发性HSV角膜炎。3名儿童发生弱视。
结论
疱疹性角膜炎患儿可能双眼受累，并有复发性角膜炎和弱视的风险。
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