Chong Eva-Marie, Wilhelmus Kirk R, Matoba Alice Y, Jones Dan B, Coats David K, Paysse Evelyn A
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, 6565 Fannin Street, Houston, TX 77030, USA.
Am J Ophthalmol. 2004 Sep;138(3):474-5. doi: 10.1016/j.ajo.2004.04.027.
To describe the spectrum and recurrence of herpes simplex virus (HSV) keratitis in children and adolescents.
Retrospective cohort study.
Twenty-three patients younger than age 16 years were diagnosed with HSV keratitis at one institution.
All children presented with dendritic or punctate epithelial keratitis, and stromal keratitis occurred concurrently with epithelial keratitis in 14 patients (61%). Six patients (26%) had bilateral HSV keratitis. Eleven patients (48%) developed recurrent HSV keratitis at a median of 15 months after the first documented episode. Amblyopia occurred in three children.
Children with herpetic keratitis may have bilateral ocular involvement and are at risk for recurrent keratitis and amblyopia.
描述儿童和青少年单纯疱疹病毒（HSV）角膜炎的范围及复发情况。
回顾性队列研究。
在一家机构中，23名16岁以下患者被诊断为HSV角膜炎。
所有儿童均表现为树枝状或点状上皮性角膜炎，14例（61%）患者基质性角膜炎与上皮性角膜炎同时发生。6例（26%）患者为双侧HSV角膜炎。11例（48%）患者在首次记录发病后的中位时间15个月出现复发性HSV角膜炎。3名儿童发生弱视。
疱疹性角膜炎患儿可能双眼受累，并有复发性角膜炎和弱视的风险。
