朗格汉斯细胞组织细胞增多症在一名成年患者中表现为角膜缘结节。
Langerhans cell histiocytosis presenting as a limbal nodule in an adult patient.
作者信息
Saxena Tishu, Kumar Krishna, Sen Seema, Tandon Radhika
机构信息
Cornea and Refractive Surgery Services, Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India.
出版信息
Am J Ophthalmol. 2004 Sep;138(3):508-10. doi: 10.1016/j.ajo.2004.04.029.
PURPOSE
To report a case of Langerhans cell histiocytosis presenting as a limbal nodule.
DESIGN
Observational case report.
METHOD
A 26-year-old man presented with a superior limbal mass. On clinical examination, an infiltrative/neoplastic lesion was suspected, and a differential diagnosis of limbal amyloidosis, limbal fibrous histiocytoma, lymphoma, and juvenile xanthogranuloma was made. There was no other associated ocular or systemic abnormality. An excision biopsy was performed.
RESULTS
The histopathology and immunohistochemical staining examination established the diagnosis of limbal Langerhans cell histiocytosis.
CONCLUSION
To the best of our knowledge, this is an unusual presentation of Langerhans cell histiocytosis, and although rare, Langerhans cell histiocytosis should be included in the differential diagnosis of a limbal mass.
目的
报告一例表现为角膜缘结节的朗格汉斯细胞组织细胞增多症病例。
设计
观察性病例报告。
方法
一名26岁男性患者出现角膜上缘肿物。临床检查怀疑为浸润性/肿瘤性病变，鉴别诊断包括角膜缘淀粉样变性、角膜缘纤维组织细胞瘤、淋巴瘤和幼年性黄色肉芽肿。未发现其他相关眼部或全身异常。进行了切除活检。
结果
组织病理学和免疫组化染色检查确诊为角膜缘朗格汉斯细胞组织细胞增多症。
结论
据我们所知，这是朗格汉斯细胞组织细胞增多症的一种不寻常表现，尽管罕见，但朗格汉斯细胞组织细胞增多症应纳入角膜缘肿物的鉴别诊断。
Zotero 插件