Emin A Haluk, Süoğlu Yusufhan, Demir Deniz, Karatay Mesut Can
Department of ORL, Faculty of Medicine, Capa-Istanbul, Turkey.
Auris Nasus Larynx. 2004 Sep;31(3):299-304. doi: 10.1016/j.anl.2004.03.014.
Brown tumor is a rare clinical entity complicating hyperparathyroidism. It may occur in the head and neck, with the mandible being the most frequent site. Hyperparathyroidism is usually associated with hypercalcemia. We report a case of madibular Brown tumor secondary to primary hyperparathyroidism. In this case in spite of hyperparathyroidism and the bony lesion the serum calcium level was within normal range. The case managed by surgical excision of the mandibular tumor with an en-bloc hemithyroidectomy with inclusion of the diseased parathyroid gland. This case demonstrates that in osteolytic bony lesions a hyperparathyroid complication can be expected even with normal serum calcium level. The presence of normocalcemia in primary hyperparathyroidism should prompt the physician to look for vitamin D deficiency.
棕色瘤是一种使甲状旁腺功能亢进复杂化的罕见临床病症。它可能发生于头颈部，下颌骨是最常见的部位。甲状旁腺功能亢进通常与高钙血症相关。我们报告一例继发于原发性甲状旁腺功能亢进的下颌棕色瘤病例。在此病例中，尽管存在甲状旁腺功能亢进和骨病变，但血清钙水平在正常范围内。该病例通过手术切除下颌肿瘤并进行整块半甲状腺切除术，包括病变的甲状旁腺。此病例表明，在溶骨性骨病变中，即使血清钙水平正常，也可能出现甲状旁腺功能亢进并发症。原发性甲状旁腺功能亢进中血钙正常的情况应促使医生寻找维生素D缺乏症。
