Castro Carmen, Serrano M Carmen, Flores Bernardo, Espinel-Ingroff Ana, Martín-Mazuelos Estrella
Servicio de Microbiología, Hospital Universitario de Valme, Seville, Spain.
J Clin Microbiol. 2004 Sep;42(9):4358-60. doi: 10.1128/JCM.42.9.4358-4360.2004.
The susceptibilities of 63 isolates of Aspergillus spp. to voriconazole were evaluated by a modified NCCLS M38-A method and the Sensititre YeastOne method. The overall agreement was 82.5%, ranging from 100% for Aspergillus niger and Aspergillus terreus to 62.5% for Aspergillus flavus. Discrepancies between the methods were due to higher Sensititre MICs. The Sensititre YeastOne method could have potential value for susceptibility testing of Aspergillus spp. to voriconazole.
采用改良的NCCLS M38-A方法和Sensititre YeastOne方法评估了63株曲霉菌对伏立康唑的敏感性。总体符合率为82.5%,其中黑曲霉和土曲霉的符合率为100%,黄曲霉的符合率为62.5%。两种方法之间的差异是由于Sensititre法测定的最低抑菌浓度(MIC)较高。Sensititre YeastOne方法在曲霉菌对伏立康唑的药敏试验中可能具有潜在价值。