Doward Lynda C, McKenna Stephen P
Galen Research, Manchester, UK.
Value Health. 2004 Sep-Oct;7 Suppl 1:S4-8. doi: 10.1111/j.1524-4733.2004.7s102.x.
This paper considers and defines the different types of patient-reported outcomes that can be collected in clinical studies. In particular, it argues that quality of life (QoL) is a distinctly different type of outcome from Health-Related Quality of Life (HRQL). QoL is seen as providing an overall assessment of the effect of both illness and its treatment on the patient. In contrast, HRQL assesses issues that are of clinical or societal importance that may or may not cause concern to the patient. Needs-based QoL is defined and it is argued that this approach (the extent to which an individual is able to meet his or her needs) provides a good working indicator of QoL.
本文探讨并定义了临床研究中可以收集的不同类型的患者报告结局。特别是，本文认为生活质量（QoL）是一种与健康相关生活质量（HRQL）截然不同的结局类型。生活质量被视为对疾病及其治疗对患者的影响进行全面评估。相比之下，健康相关生活质量评估的是具有临床或社会重要性的问题，这些问题患者可能关心也可能不关心。基于需求的生活质量被定义，并且有人认为这种方法（个人满足其需求的程度）为生活质量提供了一个良好的实用指标。
