McKenna Stephen P, Doward Lynda C
Galen Research, Manchester, UK.
Value Health. 2004 Sep-Oct;7 Suppl 1:S9-12. doi: 10.1111/j.1524-4733.2004.7s103.x.
This paper discusses the relations between different types of patient-reported outcomes that may be collected in clinical studies. Two models are presented that argue that there is a linear relation between the different outcomes. When needs-based quality of life (QoL) is incorporated into the model it is proposed that a two-dimensional relation is more appropriate. The new model is illustrated by data collected using different types of outcome measures. Finally, the different outcomes are related to their purpose in clinical studies.
本文讨论了临床研究中可能收集的不同类型患者报告结局之间的关系。提出了两种模型，认为不同结局之间存在线性关系。当将基于需求的生活质量（QoL）纳入模型时，有人提出二维关系更为合适。使用不同类型的结局测量方法收集的数据对新模型进行了说明。最后，将不同结局与其在临床研究中的目的联系起来。
