Butterworth Jeffrey R, Banfield Luke M, Iqbal Tariq H, Cooper Brian T
Gastroenterology Unit, City Hospital, Dudley Road, Birmingham, B18 7QH, England, UK.
Clin Nutr. 2004 Oct;23(5):1127-34. doi: 10.1016/j.clnu.2004.02.009.
BACKGROUND & AIMS: To identify factors relating to compliance with a gluten-free diet amongst white Caucasian and South Asians with coeliac disease.
Cross-sectional survey, with case note review of 130 adult patients with coeliac disease (90 white Caucasian and 40 South Asians).
87 (66.9%) of the 130 questionnaires were returned; whites: 73.3%, South Asians: 52.5% (P = 0.02). White Caucasians' assessment of their own strictness to the gluten-free diet correlated with small bowel histological recovery (OR 10.00, 95% CI 3.2-33.06) and negative endomysial antibodies (OR 34.94, CI 6.58-185.40). This was not seen in the South Asian patients. Amongst the white coeliacs, factors correlating with compliance with a gluten-free diet were: Coeliac Society membership, understanding food labelling, obtaining sufficient gluten-free products, explanation by a physician, and regular dietetic follow-up. These factors were not identified amongst the South Asians, who were less likely to attend dietetic clinics, join the Coeliac Society and be satisfied with information provided by doctors and dieticians.
In contrast to the South Asians, factors were identified which related to compliance with a gluten-free diet amongst white Caucasian coeliac patients. This study has shown that the treatment approach to ethnic minorities with coeliac disease must be improved.
确定与患有乳糜泻的白种人和南亚人遵循无麸质饮食相关的因素。
横断面调查，对130例成年乳糜泻患者（90例白种人、40例南亚人）的病历进行回顾。
130份问卷中87份（66.9%）被收回；白种人：73.3%，南亚人：52.5%（P = 0.02）。白种人对自身遵循无麸质饮食严格程度的评估与小肠组织学恢复相关（比值比10.00，95%可信区间3.2 - 33.06）以及与肌内膜抗体阴性相关（比值比34.94，可信区间6.58 - 185.40）。南亚患者中未发现这种情况。在白种乳糜泻患者中，与遵循无麸质饮食相关的因素有：乳糜泻协会会员身份、理解食品标签、获得足够的无麸质产品、医生的解释以及定期的营养门诊随访。在南亚人中未发现这些因素，他们较少可能去营养门诊、加入乳糜泻协会，并且对医生和营养师提供的信息不满意。
与南亚人相比，已确定白种乳糜泻患者中与遵循无麸质饮食相关的因素。本研究表明，对患有乳糜泻的少数民族的治疗方法必须改进。
