Haupert Michael S, Pascual Clarina, Mohan Abboy, Bartecka-Skrzypek Beata, Zestos Maria M
Department of Pediatric Otolaryngology, Wayne State University School of Medicine, Children's Hospital of Michigan, Detroit, USA.
Arch Otolaryngol Head Neck Surg. 2004 Sep;130(9):1025-8. doi: 10.1001/archotol.130.9.1025.
To evaluate the effect of intravenous (i.v.) access in children undergoing bilateral myringotomy with pressure-equalizing tube placement.
One hundred healthy children were enrolled in this randomized controlled study. One group received i.v. access; the other group did not. Anesthesia in both groups was induced through a mask and maintained with oxygen, nitrous oxide, and sevoflurane. Spontaneous ventilation was maintained. All children received fentanyl, 1 microg/kg intramuscularly. Children with i.v. access received 20 mL/kg of lactated Ringer's solution. Parents were telephoned the day after surgery to report on pain and vomiting, as well as their satisfaction with anesthesia.
Tertiary care children's hospital with all procedures performed by attending pediatric otolaryngologists and otolaryngology residents. Anesthesia was administered by a pediatric anesthesiologist and a trainee.
The groups were similar in age, weight, and incidence of vomiting. Children with i.v. access spent more time than those without (mean +/- SD minutes) in the operating room (21 +/- 8 vs 17 +/- 7; P =.02), in phase 2 recovery (75 +/- 67 vs 51 +/- 24; P =.02), and in the hospital (119 +/- 67 vs 88 +/- 30; P =.005). These children also required more pain medication (31% vs 2%; P<.001) and had a lower parental satisfaction rate (28% vs 95%; P<.001).
Intravenous access in otherwise healthy children undergoing myringotomy provided no added benefit. Children without i.v. access had reduced pain requirement and spent less time in the operating room, in phase 2 recovery, and in the hospital. Parental satisfaction, a clinically relevant outcome, was significantly greater for parents of children without i.v. access.
评估静脉通路对接受双侧鼓膜切开置管术儿童的影响。
100名健康儿童纳入此项随机对照研究。一组接受静脉通路;另一组未接受。两组均通过面罩诱导麻醉,并用氧气、氧化亚氮和七氟醚维持。维持自主通气。所有儿童均肌内注射1μg/kg芬太尼。有静脉通路的儿童静脉输注20ml/kg乳酸林格氏液。术后第1天给家长打电话,报告疼痛、呕吐情况以及他们对麻醉的满意度。
三级医疗儿童医院,所有手术均由儿科耳鼻喉科主治医生和耳鼻喉科住院医师进行。麻醉由一名儿科麻醉医生和一名实习生实施。
两组在年龄、体重和呕吐发生率方面相似。有静脉通路的儿童在手术室的时间(平均±标准差,分钟)比无静脉通路的儿童更长(21±8比17±7;P = 0.02),在第二阶段恢复的时间更长(75±67比51±24;P = 0.02),住院时间更长(119±67比88±30;P = 0.005)。这些儿童还需要更多的止痛药物(31%比2%;P<0.001),家长满意度较低(28%比95%;P<0.001)。
对于接受鼓膜切开术的健康儿童,静脉通路没有额外益处。无静脉通路的儿童止痛药物需求减少,在手术室、第二阶段恢复和住院的时间更短。家长满意度是一个临床相关结果,无静脉通路儿童的家长满意度明显更高。