Murray Andrea K, Gorodkin Rachel E, Moore Tonia L, Gush Rodney J, Herrick Ariane L, King Terence A
Laser Photonics Group, University of Manchester, Manchester M13 9PL, United Kingdom.
Lasers Surg Med. 2004;35(3):191-200. doi: 10.1002/lsm.20085.
Laser Doppler imaging (LDI) of perfusion has been performed with a novel green wavelength (532 nm) for comparison with a HeNe laser (633 nm), the aim being validation of the green laser wavelength as a research tool.
STUDY DESIGN/MATERIALS AND METHODS: The effect of wavelength and power on images was investigated and perfusion response following both finger occlusion and local heating of the dorsum were examined as reproducible stimuli for clinical studies.
The most striking difference between red and green LDI is the absence of veins on green LDI, which are seen with red LDI. Differences have been quantified using vein LDI profiles. Differences were found between blood flow responses imaged by red and green LDI (3 and 5 mW, respectively) for occlusion and heat stimuli. Results are discussed in the context of light penetration.
Red and green wavelengths appear to image different components of the microcirculation.
已使用新型绿色波长(532纳米)进行灌注的激光多普勒成像(LDI),以与氦氖激光(633纳米)进行比较,目的是验证绿色激光波长作为一种研究工具。
研究设计/材料与方法:研究了波长和功率对图像的影响,并检查了手指闭塞和背部局部加热后作为临床研究可重复刺激的灌注反应。
红色和绿色LDI之间最显著的差异是绿色LDI上没有静脉,而红色LDI上可见静脉。已使用静脉LDI轮廓对差异进行了量化。在闭塞和热刺激时,红色和绿色LDI(分别为3和5毫瓦)成像的血流反应之间存在差异。在光穿透的背景下讨论了结果。
红色和绿色波长似乎成像微循环的不同成分。