Street D A, Javitt J C
Worthen Center for Eye Care Research, Center for Sight, Georgetown University Medical Center, Washington, D.C.
Am J Ophthalmol. 1992 Mar 15;113(3):263-8. doi: 10.1016/s0002-9394(14)71577-6.
We assessed the five-year mortality in all United States Medicare beneficiaries aged 65 to 79 years who underwent inpatient cataract extraction in 1984. The risk of dying within five years after cataract extraction was compared to the five-year mortality risk of the same aged persons in the United States population. Patients with cataracts who were younger than 75 years had significantly higher age-specific rates of mortality than would be predicted from United States life tables (P less than .001). For example, at the age of 65 years, patients with cataracts had 1.34 times the risk of the United States population (95% confidence interval = 1.29 to 1.41). This risk progressively declined until the age of 75 years, at which age there is little difference between the patients with cataracts and the United States population, except for the oldest women with cataracts (at the age of 79 years, relative risk = .90; 95% confidence interval = .82 to .99). Although selection factors may account for the excess mortality observed among these individuals, these data do support previous analyses that suggest an association between senile cataract and increased risk of mortality.
我们评估了1984年接受住院白内障摘除手术的所有65至79岁美国医疗保险受益人的五年死亡率。将白内障摘除术后五年内死亡风险与美国同年龄段人群的五年死亡率风险进行了比较。年龄小于75岁的白内障患者的年龄特异性死亡率显著高于根据美国生命表预测的死亡率（P小于0.001）。例如，65岁时，白内障患者的风险是美国人群的1.34倍（95%置信区间=1.29至1.41）。这种风险逐渐下降，直到75岁，此时白内障患者与美国人群之间几乎没有差异，但年龄最大的患有白内障的女性除外（79岁时，相对风险=0.90；95%置信区间=0.82至0.99）。尽管选择因素可能解释了在这些个体中观察到的额外死亡率，但这些数据确实支持了先前的分析，即表明老年性白内障与死亡风险增加之间存在关联。
