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青光眼和白内障患者的无症状心肌缺血

Silent myocardial ischemia in glaucoma and cataract patients.

作者信息

Waldmann E, Gasser P, Dubler B, Huber C, Flammer J

机构信息

University Eye Clinic, Basel, Switzerland.

出版信息

Graefes Arch Clin Exp Ophthalmol. 1996 Oct;234(10):595-8. doi: 10.1007/BF00185290.

DOI:10.1007/BF00185290
PMID:8897049
Abstract

BACKGROUND

Glaucoma and cataract are multifactorial diseases. They have been described to be associated with cardiovascular risk factors.

METHODS

Twenty-four-hour ECG monitoring was done in 22 normal-tension glaucoma patients, 27 open-angle glaucoma patients, 25 cataract patients, and 20 normal controls. The frequency of silent myocardial ischemia (SMI) as well as that of ventricular extrasystoles (VES) was evaluated.

RESULTS

At least one episode of significant asymptomatic ST-T segment depression occurred in 45% of the normal-tension glaucomas, in 25.9% of open-angle glaucomas, in 12% of cataract patients, and in 5% of normal controls. The frequency of VES was not significantly different among the groups.

CONCLUSIONS

Glaucoma, especially normal-tension glaucoma, is significantly associated with the occurrence of episodic asymptomatic myocardial ischemias. Cataract patients, however, had only a slightly, statistically not significantly increased frequency of both SMI and VES compared with normals.

摘要

背景

青光眼和白内障是多因素疾病。它们被描述为与心血管危险因素相关。

方法

对22例正常眼压性青光眼患者、27例开角型青光眼患者、25例白内障患者和20例正常对照者进行24小时心电图监测。评估无症状心肌缺血(SMI)以及室性期前收缩(VES)的发生率。

结果

45%的正常眼压性青光眼患者、25.9%的开角型青光眼患者、12%的白内障患者和5%的正常对照者至少发生过一次显著的无症状ST-T段压低。各组间VES的发生率无显著差异。

结论

青光眼,尤其是正常眼压性青光眼,与偶发性无症状心肌缺血的发生显著相关。然而,与正常人相比,白内障患者的SMI和VES发生率仅略有增加,统计学上无显著差异。

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