Hopt U T, Makowiec F, Adam U
Abteilung Allgemein- und Viszeralchirurgie, Chirurgische Universitätsklinik Freiburg.
Chirurg. 2004 Nov;75(11):1079-87. doi: 10.1007/s00104-004-0946-1.
The frequency of anastomotic leaks after pancreatic resection is still significant. The majority of such leaks will heal without major clinical symptoms. In one fifth of patients, however, the sequelae of pancreatic leakage are serious and sometimes life-threatening. Management of such leaks ranges from local drainage to operative revision and completion pancreatectomy. The frequency of anastomotic leakage depends on a series of patient- and organ-specific risk factors. Surgical experience also plays a major role. Whether the prophylactic application of octreotide is able to reduce the frequency of pancreatic leaks is still a matter of debate. Leaks from direct bile duct sutures or biliodigestive anastomoses are rather seldom. Their clinical importance is limited. In case of a leak after direct bile duct anastomosis, endoscopic insertion of a stent seems to be the therapy of choice. Leaks from biliodigestive anastomoses which are diagnosed during the first 3 postoperative days should be treated by immediate operative revision. Late biliary leaks can be treated by local drainage. The results of bile duct surgery, too, are clearly dependent on the experience of the operating surgeon.
胰腺切除术后吻合口漏的发生率仍然较高。大多数此类漏口可在无重大临床症状的情况下愈合。然而,在五分之一的患者中,胰漏的后遗症很严重,有时甚至危及生命。此类漏口的处理方法包括局部引流、手术修复和全胰切除术。吻合口漏的发生率取决于一系列患者和器官特异性危险因素。手术经验也起着重要作用。奥曲肽的预防性应用是否能够降低胰漏的发生率仍存在争议。直接胆管缝合或胆肠吻合口漏相当少见。其临床重要性有限。对于直接胆管吻合术后的漏口,内镜下置入支架似乎是首选治疗方法。术后前3天诊断出的胆肠吻合口漏应立即进行手术修复。晚期胆漏可通过局部引流治疗。胆管手术的结果也明显取决于手术医生的经验。