Kasaboğlu Oğuzcan, Er Nuray, Tümer Celal, Akkocaoğlu Murat
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Hacettepe University, 06100 Sihhiye/Ankara, Turkey.
J Oral Maxillofac Surg. 2004 Oct;62(10):1253-8. doi: 10.1016/j.joms.2003.11.018.
Sialoliths are common in the submandibular gland and its duct system. The exact cause of formation of a sialolith is still a matter of debate. The aim of this study was to analyze 6 sialoliths ultrastructurally to determine their development mechanism in the submandibular salivary glands.
Six sialoliths retrieved from the hilus and duct of the submandibular salivary glands of 6 patients with sialadenitis were analyzed ultrastructurally by scanning electron microscope and x-ray diffractometer.
Scanning electron microscope revealed mainly irregular, partly rudely hexagonal, needle-like and plate-shaped crystals. The cross-section from the surface to the inner part of the sialoliths showed no organic material. X-ray diffraction showed that the sialoliths were composed of hydroxyapatite crystals. Energy dispersive x-ray microanalysis showed that all of the samples contained high levels of Ca and P, and small amounts of Mg, Na, Cl, Si, Fe, and K.
The main structures of the submandibular sialoliths were found to be hydroxyapatite crystals. No organic cores were observed in the central parts of the sialoliths. In accordance with these preliminary results, sialoliths in the submandibular salivary glands may arise secondary to sialadenitis, but not via a luminal organic nidus.
涎石在下颌下腺及其导管系统中很常见。涎石形成的确切原因仍存在争议。本研究的目的是对6颗涎石进行超微结构分析，以确定它们在下颌下唾液腺中的形成机制。
从6例涎腺炎患者的下颌下唾液腺门部和导管中取出6颗涎石，用扫描电子显微镜和X射线衍射仪进行超微结构分析。
扫描电子显微镜显示主要为不规则、部分呈粗糙六边形、针状和板状晶体。涎石从表面到内部的横截面未显示有机物质。X射线衍射显示涎石由羟基磷灰石晶体组成。能量色散X射线微分析显示，所有样品都含有高水平的钙和磷，以及少量的镁、钠、氯、硅、铁和钾。
发现下颌下涎石的主要结构是羟基磷灰石晶体。在涎石的中心部分未观察到有机核心。根据这些初步结果，下颌下唾液腺中的涎石可能继发于涎腺炎，但不是通过管腔内的有机病灶形成。
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