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儿童涎石病的组织病理学和超微结构研究结果:简要通讯

Histopathology and ultrastructural findings of pediatric sialolithiasis: a brief communication.

作者信息

Mustakim Kezia Rachellea, Nguyen Truc Thi Hoang, Eo Mi Young, Kim Soung Min

机构信息

Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.

Oral and Maxillofacial Microvascular Reconstruction LAB, Brong Ahafo Regional Hospital, Sunyani, Ghana.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2022 Apr 30;48(2):125-129. doi: 10.5125/jkaoms.2022.48.2.125.

Abstract

Sialolithiasis is a condition in which the salivary gland excretory duct is obstructed due to the formation of calcareous deposits and is uncommon in children compared to adults. The treatment modalities range from a conservative approach involving hydration to a surgical approach. Though several studies have analyzed the sialolith micromorphology structures, studies on pediatric sialoliths remain scarce. This brief communication aims to describe the sialolith micromorphology to understand the mechanism of mineralization and growth of pediatric sialoliths. A 6-year-old Korean female presented with swelling under her tongue. The intraoral examination revealed a painless yellowish hard mass beneath the tongue near the Wharton's duct which was suspected as a sialolith. After receiving the informed consent, the sialolithotomy was performed under local anesthesia. The obtained stone was analyzed through histopathology and transmission electron microscope examinations to understand the mechanism of mineralization and growth of pediatric sialolith. The micromorphology and growth processes of pediatric sialolith remain undescribed. More comprehensive microscopic studies are needed regarding their distinctive characteristics. By expanding knowledge about sialoliths micromorphology, development of new preventive, diagnostic and patient-tailored treatment methods of pediatric sialolithiasis will be enhanced.

摘要

涎石病是一种由于钙质沉积物形成而导致唾液腺排泄管阻塞的疾病,与成人相比在儿童中并不常见。治疗方式从包括补水的保守方法到手术方法不等。尽管有几项研究分析了涎石的微观形态结构,但关于儿童涎石的研究仍然很少。这篇简短的通讯旨在描述涎石的微观形态,以了解儿童涎石矿化和生长的机制。一名6岁韩国女性因舌下肿胀就诊。口腔检查发现舌下靠近颌下腺导管处有一个无痛的淡黄色硬块,怀疑是涎石。在获得知情同意后,在局部麻醉下进行了涎石切除术。对取出的结石进行了组织病理学和透射电子显微镜检查,以了解儿童涎石矿化和生长的机制。儿童涎石的微观形态和生长过程仍未得到描述。需要对其独特特征进行更全面的微观研究。通过扩展对涎石微观形态的认识,将加强儿童涎石病新的预防、诊断和针对患者的治疗方法的开发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e717/9065641/2478993f6803/jkaoms-48-2-125-f1.jpg

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