Gemelli A, Marilungo M, De Ruvo S, Falcone M, Gemelli F, Sasdelli M, Lo Sardo G, Vallone M, Re M, Clemenzia G
Servizio di Cardiologia, USL RM 2, Policlinico Umberto I, Roma.
Minerva Med. 1992 Jan-Feb;83(1-2):9-16.
The paper reports an electrocardiographic and M and B-mode echocardiographical study in 3682 non-selected patients among which a total of 241 were identified with mitral valve prolapse. In males the highest frequency was found during the second decade of life with a tendency to decrease with increasing age. In females, who were found to be the most severely affected (2:1 in relation to males), two peaks of incidence were observed during the third and fifth decade, with a greater frequency in the latter and a marked absence of cases in the fourth decade. Many echocardiographically diagnosed mitral prolapses were both clinically and electrocardiographically silent; moreover it was observed that the risks of this complication increased in parallel to the thinness and redundance of the mitralic flap affected by prolapse and the dilation of the valvular ring.
该论文报告了对3682例未经挑选的患者进行的心电图及M型和B型超声心动图研究，其中共有241例被诊断为二尖瓣脱垂。在男性中，最高发病频率出现在第二个十年，且有随年龄增长而下降的趋势。在女性中，她们被发现受影响最为严重（男女比例为2:1），在第三个和第五个十年观察到两个发病高峰，后者的频率更高，且在第四个十年明显没有病例。许多经超声心动图诊断的二尖瓣脱垂在临床和心电图上均无表现；此外，观察到这种并发症的风险与受脱垂影响的二尖瓣瓣叶的变薄和冗余以及瓣膜环的扩张平行增加。
