McCarthy James, Arrese Diana, McGlashan Alexandra, Rappaport Brad, Kraseski Keith, Conway Francine, Mule Carmelina, Tucker Jennifer
Queens Children's Psychiatric Center, Bellerose, NY 11426, USA.
Psychol Rep. 2004 Aug;95(1):39-47. doi: 10.2466/pr0.95.1.39-47.
To investigate the cognitive functioning of children and adolescents with bipolar illness, 112 child and adolescent psychiatric inpatients and day-hospital patients at a state psychiatric hospital were administered the Wechsler Intelligence Scale for Children-III (WISC-III) as part of an admission psychological assessment. There were 22 patients with Bipolar Disorder and 90 with other psychiatric disorders; all were between 8 and 17 years of age. The patients with Bipolar Disorder had a mean age of 14 yr., a mean Verbal IQ of 78, a mean Performance IQ of 76, and a mean Full Scale IQ of 75. When their WISC-III scores were compared with those who had Schizophrenia Spectrum disorders (Schizophrenia and Schizoaffective Disorder), Psychosis Not Otherwise Specified, Attention Deficit Hyperactivity Disorder, and Conduct Disorder and Oppositional Defiant Disorder, there were no significant between-group mean differences for Verbal IQ, but patients with Bipolar Disorder had a significantly lower mean Performance IQ than those with ADHD and those with Conduct Disorder and Oppositional Defiant Disorder. Contrary to the expectation that the patients with Bipolar Disorder might have better sustained attention (higher Digit Span scores) than those with Schizophrenia Spectrum disorders and worse visual processing speed (lower Coding scores) than the other diagnostic groups, the bipolar patients' Digit Span and Coding scores did not differ significantly from those of the other groups. The patients with Psychosis, Not Otherwise Specified had significantly lower mean Performance IQ, Full Scale IQ, and Coding than the ADHD and the Conduct Disorder and Oppositional Disorder groups.
为了研究双相情感障碍儿童和青少年的认知功能，一家州立精神病医院对112名儿童和青少年精神科住院患者及日间医院患者进行了韦氏儿童智力量表第三版（WISC-III）测试，作为入院心理评估的一部分。其中有22名双相情感障碍患者和90名患有其他精神障碍的患者；所有患者年龄在8至17岁之间。双相情感障碍患者的平均年龄为14岁，言语智商平均为78，操作智商平均为76，总智商平均为75。当将他们的WISC-III分数与患有精神分裂症谱系障碍（精神分裂症和分裂情感性障碍）、未特定的精神病性障碍、注意力缺陷多动障碍以及品行障碍和对立违抗障碍的患者进行比较时，言语智商在组间平均差异不显著，但双相情感障碍患者的操作智商平均显著低于患有注意力缺陷多动障碍以及品行障碍和对立违抗障碍的患者。与预期相反，即双相情感障碍患者可能比精神分裂症谱系障碍患者有更好的持续注意力（数字广度得分更高），并且比其他诊断组有更差的视觉处理速度（编码得分更低），双相情感障碍患者的数字广度和编码得分与其他组没有显著差异。未特定的精神病性障碍患者的操作智商、总智商和编码得分平均显著低于注意力缺陷多动障碍以及品行障碍和对立障碍组。
