Design considerations for an ontology in the domain of organ failure and transplantation.

The Etablissement français des Greffes (EfG) is a national agency dealing with Public Health issues related to organ, tissue and cell transplantation in France. The evaluation of organ retrieval and transplantation activities, one of its missions, is supported by a national information system (IS). In order to facilitate data recording, to improve the quality of information and to prepare semantic interoperability with other information systems, the existing thesaurus of the EfG was audited, leading to the design a new terminological module devoted to the support of the domain ontology.