Warkentin S, Nilsson A, Karlson S, Risberg J, Franze'n G, Gustafson L
Department of Psychiatry, University of Lund, Sweden.
Acta Psychiatr Scand. 1992 Jan;85(1):23-9. doi: 10.1111/j.1600-0447.1992.tb01437.x.
Eight patients meeting Leonhard's criteria for cycloid psychosis were investigated on repeated occasions during a psychotic episode, with regional cerebral blood flow measurements and clinical ratings. The results showed that, at admission to the hospital, when the patients were clinically exacerbated, the mean hemispheric blood flow was significantly elevated compared with values from a normal control group. The hemispheric blood flow level covaried significantly with the degree of clinical symptoms, such that the more elevated the cortical blood flow was, the more behaviorally disturbed was the patient. At discharge from the hospital, the patients had no residual symptoms and the cortical blood flow was normal. These findings differ distinctly from those commonly made in other psychoses, such as schizophrenia.
对八名符合莱昂哈德环性精神病标准的患者在精神病发作期间进行了多次调查，采用了局部脑血流测量和临床评分方法。结果显示，入院时，患者临床症状加重，与正常对照组相比，平均半球血流量显著升高。半球血流量水平与临床症状程度显著相关，即皮质血流量升高越多，患者行为紊乱越严重。出院时，患者无残留症状，皮质血流量正常。这些发现与其他精神病（如精神分裂症）的常见发现明显不同。
