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消退的条件反应的恢复以及负性刺激效价作为人类恐惧复发的一条途径。

Reinstatement of extinguished conditioned responses and negative stimulus valence as a pathway to return of fear in humans.

作者信息

Dirikx Trinette, Hermans Dirk, Vansteenwegen Debora, Baeyens Frank, Eelen Paul

机构信息

Department of Psychology, University of Leuven, Leuven 3000, Belgium.

出版信息

Learn Mem. 2004 Sep-Oct;11(5):549-54. doi: 10.1101/lm.78004.

DOI:10.1101/lm.78004
PMID:15466307
Abstract

The present study investigated reinstatement of conditioned responses in humans by using a differential Pavlovian conditioning procedure. Evidence for reinstatement was established in a direct (fear rating) and in an indirect measure (secondary reaction time task) of conditioning. Moreover, the amount of reinstatement in the secondary reaction time task was significantly correlated with the difference in valence between the conditioned stimulus (CS)+ and the CS-after extinction. These data provide clear evidence for reinstatement and for the role of negative stimulus valence in the return of conditioned responding after extinction.

摘要

本研究采用差异巴甫洛夫条件反射程序,调查了人类条件反应的恢复情况。通过对条件反射的直接测量(恐惧评分)和间接测量(次级反应时任务),证实了恢复的证据。此外,次级反应时任务中的恢复量与条件刺激(CS)+和消退后的CS之间的效价差异显著相关。这些数据为恢复以及负性刺激效价在消退后条件反应恢复中的作用提供了明确证据。

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