Stafford Christopher M, Herndier Brian, Yi Eunhee S, Weidner Noel, Harrell James H
Department of Internal Medicine, Division of Pulmonary/Critical Care Medicine, Naval Medical Center San Diego, San Diego, Calif. 92134-1005, USA.
Respiration. 2004 Sep-Oct;71(5):529-32. doi: 10.1159/000080641.
Granulocytic sarcoma (GS) is an extramedullary, solid tumor composed of immature granulocytic cells, which occurs in association with myeloproliferative or leukemic disorders. GS can precede, accompany, or complicate the presence of hematologic malignancy in the blood or bone marrow. The anatomic distribution commonly includes bone, nerve, lymph node, and skin, but may involve a variety of soft tissues. Pulmonary involvement is uncommon but may invade the parenchyma, pleura, mediastinum, and airways. We report a rare case of endobronchial granulocytic sarcoma with bronchoscopic and pathologic correlation.
粒细胞肉瘤(GS)是一种由未成熟粒细胞组成的髓外实体瘤,与骨髓增殖性疾病或白血病相关。GS可先于血液或骨髓中的血液系统恶性肿瘤出现、与之伴随或使其复杂化。其解剖分布通常包括骨骼、神经、淋巴结和皮肤,但也可能累及多种软组织。肺部受累并不常见,但可能侵犯实质、胸膜、纵隔和气道。我们报告一例罕见的支气管内粒细胞肉瘤病例,并进行支气管镜检查及病理对照。