Benetou Vassiliki, Bamia Christina, Trichopoulos Dimitrios, Mountokalakis Theodoros, Psaltopoulou Theodora, Trichopoulou Antonia
Department of Hygiene and Epidemiology, University of Athens, Medical School, Athens, Greece.
Eur J Epidemiol. 2004;19(8):803-9. doi: 10.1023/b:ejep.0000036582.38987.ca.
Body mass index (BMI) and waist circumference are independently associated with blood pressure, but the dependence of these associations on gender and age has not been clarified. We investigated the associations of BMI and waist circumference with systolic (SBP) and diastolic (DBP) blood pressure and assessed possible interactions with gender and age. Data concerning blood pressure and anthropometric variables were collected at enrollment in a cohort study from 10,928 non-smoking adults, all over Greece, who have never received antihypertensive treatment. Multiple regression-derived standardized coefficients were estimated to compare effects among variables. Among men, waist circumference appears more important than BMI in the prediction of SBP (standardized coefficients 2.26 vs. 1.52 mmHg/SD), and to a lesser extent DBP. In contrast, among women, BMI is more important than waist circumference, in the prediction of SBP (standardized coefficients 3.97 vs. 1.56 mmHg/ SD) and to a lesser extent DBP. The different effects of BMI and waist circumference on blood pressure by gender are evident among older individuals (> 55 years); among younger individuals BMI and waist circumference have comparable effects in both genders. Among younger individuals, BMI and waist circumference are independent and equally important predictors of SBP and DBP in both genders, whereas among older individuals waist circumference is the dominant predictor of blood pressure among men and BMI is the dominant predictor of blood pressure among women. Associations are more evident with respect to SBP than DBP.
体重指数（BMI）和腰围均与血压独立相关，但这些关联对性别和年龄的依赖性尚未明确。我们研究了BMI和腰围与收缩压（SBP）和舒张压（DBP）之间的关联，并评估了与性别和年龄可能存在的相互作用。在一项队列研究的入组阶段，收集了希腊各地10928名从未接受过降压治疗的非吸烟成年人的血压及人体测量学变量数据。通过多元回归得出标准化系数，以比较各变量之间的效应。在男性中，腰围在预测SBP方面似乎比BMI更重要（标准化系数分别为2.26和1.52 mmHg/标准差），对DBP的预测重要性稍低。相比之下，在女性中，BMI在预测SBP方面比腰围更重要（标准化系数分别为3.97和1.56 mmHg/标准差），对DBP的预测重要性稍低。BMI和腰围对血压的不同影响在老年个体（>55岁）中按性别表现明显；在年轻个体中，BMI和腰围在两性中的影响相当。在年轻个体中，BMI和腰围是两性SBP和DBP的独立且同等重要的预测因素，而在老年个体中，腰围是男性血压的主要预测因素，BMI是女性血压的主要预测因素。与DBP相比，这些关联在SBP方面更为明显。
