Chou Kelvin L, Siderowf Andrew D, Jaggi Jurg L, Liang Grace S, Baltuch Gordon H
Department of Clinical Neurosciences, Brown University School of Medicine, Providence, RI, USA.
Stereotact Funct Neurosurg. 2004;82(4):153-5. doi: 10.1159/000081348. Epub 2004 Oct 5.
We describe 2 patients with advanced Parkinson's disease (PD) treated with bilateral deep brain stimulation of the subthalamic nucleus in whom unilateral stimulator battery depletion resulted in the rapid appearance of disabling PD symptoms (severe rigidity, bradykinesia and gait difficulty). Both patients did not respond to high doses of dopaminergic medications and were restored to their previous level of function only with battery replacement. One patient developed a deep vein thrombosis and pulmonary emboli as a result of prolonged immobility. Although extreme worsening of PD secondary to battery depletion may be rare, such patients should have their stimulators replaced promptly.
我们描述了2例晚期帕金森病（PD）患者，他们接受了双侧丘脑底核深部脑刺激治疗，其中单侧刺激器电池耗尽导致致残性PD症状（严重僵硬、运动迟缓及步态困难）迅速出现。两名患者对高剂量多巴胺能药物均无反应，仅通过更换电池才恢复到先前的功能水平。一名患者因长期不动而发生深静脉血栓形成和肺栓塞。尽管因电池耗尽导致PD极度恶化可能很罕见，但此类患者应及时更换刺激器。
