Aldinger P R, Clarius M, Murray D W, Goodfellow J W, Breusch S J
Orthopädische Universitätsklinik, Heidelberg.
Orthopade. 2004 Nov;33(11):1277-83. doi: 10.1007/s00132-004-0712-6.
Medial unicompartmental knee replacement (UKR) has many advantages over total replacement (TKR) including better function and reduced morbidity. However, the long-term failure rates of fixed-bearing UKR are high, especially because of polyethylene wear. The fully congruent mobile bearing of the Oxford UKR exhibits minimal polyethylene wear, failure from this cause does not seem to occur before 10 years. The instrumentation allows precise implantation to restore isometric function of the ligaments. During its 20 years development, the limits of usefulness of the implant have been established and found to include about one in four knees requiring replacement for osteoarthritis. In an independent series, using these criteria, the 15 year survival was 94%. Since 1998, the phase 3 implant has been used with modified instruments through a small incision, avoiding damage to the extensor mechanism. Patients now recover about three times faster than after TKR, and regain much better flexion (mean 135 degrees ). The current evidence supports that the minimally invasive Oxford UKR should be seriously considered as primary treatment for anteromedial compartment osteoarthritis-provided the appropriate surgical expertise is available.
内侧单髁膝关节置换术(UKR)与全膝关节置换术(TKR)相比有许多优势,包括更好的功能和更低的发病率。然而,固定平台UKR的长期失败率很高,尤其是由于聚乙烯磨损。牛津UKR的全贴合活动平台聚乙烯磨损极小,10年内似乎不会因这种原因出现失败。该手术器械可实现精确植入,以恢复韧带的等距功能。在其20年的发展过程中,已确定了该植入物的适用范围,发现约四分之一因骨关节炎需要置换的膝关节适用。在一个独立的系列研究中,按照这些标准,15年生存率为94%。自1998年以来,通过小切口使用改良器械植入3期植入物,避免了对伸肌机制的损伤。现在患者恢复速度比TKR后快约三倍,并且能获得更好的屈曲度(平均135度)。目前的证据支持,在具备适当手术专业技能的情况下,微创牛津UKR应被认真考虑作为前内侧间室骨关节炎的主要治疗方法。